After 15 seasons, CSI is out at CBS. Here's what's replacing it this fall.

The case of original-flavor CSI is officially closed: CBS has unveiled its fall 2015 schedule, and one of its first orders of business will be to wrap up the long-running crime procedural with a two-hour series finale on Sunday, September 27. Many of the show's original cast members are expected to return for the occasion. After the finale, current star Ted Danson, who joined the series in 2011, will make the leap to the franchise's newest (and only surviving) branch, CSI: Cyber.

Elsewhere in CBS's lineup, only a few other changes are afoot, one of which is to phase out comedy from Monday nights. The network is dipping its toe into the superpowered waters of comic-book-based TV with new drama Supergirl, which will lead off the workweek on Mondays at 8 pm beginning in November. Other new series include a comedy starring Jane Lynch and an adaptation of the Bradley Cooper film Limitless, which Cooper will executive-produce and recur on as a guest star.

In late night, Stephen Colbert will begin his tenure on Late Show on Tuesday, September 8.

Sitting on the bench for fall are Person of Interest, 2 Broke Girls, Mike & Molly, The Odd Couple, and Undercover Boss, all of which will return in early 2016 alongside new shows that include a Criminal Minds spinoff and a reimagining of the Rush Hour feature film franchise.

Read on to find out what's airing when, and to watch trailers for CBS's new shows.

MONDAY

(September and October)

8 to 8:30 pm — The Big Bang Theory

8:30 to 9 pm — Life in Pieces is a new comedy the network is billing as "one big happy family and their sometimes awkward, often hilarious, and ultimately beautiful milestone moments as told by its various members." Each episode will contain four short stories, and the series' ensemble cast boasts Dianne Wiest, James Brolin, Colin Hanks, Betsy Brandt (Breaking Bad), Thomas Sadoski (The Newsroom), Dan Bakkedahl (Veep), and Zoe Lister Jones (New Girl). Think Parenthood but with more jokes. Watch a trailer below:

9 to 10 pm — Scorpion

10 to 11 pm — NCIS: Los Angeles

(November)

8 to 9 pm — It's a bird, it's a plane, it's a superhero show on CBS! New drama Supergirl is based on the DC Comics character and cousin to Superman, Kara Zor-El (Glee's Melissa Benoist), who, after 12 years keeping her powers a secret on Earth, decides to finally embrace her special abilities and become the hero she was always meant to be. The series is executive-produced by Greg Berlanti, who also executive-produces The Flash and Arrow on CBS's sister network The CW. Watch a trailer below:

9 to 10 pm — Scorpion

10 to 11 pm — NCIS: Los Angeles

TUESDAY

8 to 9 pm — NCIS

9 to 10 pm — NCIS: New Orleans

10 to 11 pm — New drama Limitless is based on the 2011 movie about a man who discovers the brain-boosting power of a mysterious drug and is coerced by the FBI into using his extraordinary cognitive abilities to solve complex cases. Jake McDorman, Jennifer Carpenter (Dexter), Hill Harper, and Mary Elizabeth Mastrantonio star, with executive producer and original film star Bradley Cooper occasionally dropping by as a guest. Watch a trailer below:

WEDNESDAY

8 to 9 pm — Survivor

9 to 10 pm — Criminal Minds

10 to 11 pm — New scripted medical drama Code Black is based on a documentary of the same name and set in the one of the country's busiest ERs, which for television purposes is home to all the usual medical-drama suspects, including world-renowned physicians, rookie residents, a seen-it-all nurse, and at least one doc who's known for a "cowboy" approach. Marcia Gay Harden stars. Watch a trailer below:

THURSDAY

(September and October)

8 to 11 pm — Thursday Night Football

(November)

8 to 8:30 pm — The Big Bang Theory

8:30 to 9 pm — Life in Pieces

9 to 9:30 pm — Mom

9:30 to 10 pm — Angel From Hell stars Jane Lynch as Amy, the titular "angel" who proclaims to be the guardian of a young, ambitious doctor named Allison (Maggie Lawson). You can probably guess how the premise unfolds: Amy shows up unexpectedly in Allison's life spouting so-called wisdom, Allison assumes Amy is a nutjob, and then all of Amy's predictions/warnings come true. It's a tried-and-true "unlikely partnership" story with a dash of feel-good spirituality. Watch trailer below:

10 to 11 pm — Elementary

FRIDAY

8 to 9 pm — The Amazing Race

9 to 10 pm — Hawaii Five-0

10 to 11 pm — Blue Bloods

SATURDAY

8 to 10 pm — reruns

10 to 11 pm — 48 Hours Mystery

SUNDAY

7 to 8 pm — 60 Minutes

8 to 9 pm — Madam Secretary

9 to 10 pm — The Good Wife

10 to 11 pm — CSI: Cyber

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